A Positive Urine Alcohol with Negative Urine Ethyl-Glucuronide
نویسندگان
چکیده
منابع مشابه
Postcollection synthesis of ethyl glucuronide by bacteria in urine may cause false identification of alcohol consumption.
BACKGROUND Ethyl glucuronide (EtG) is a minor ethanol metabolite used as a specific marker to document recent alcohol consumption; confirm abstinence in treatment programs, workplaces, and schools; and provide legal proof of drinking. This study examined if bacterial pathogens in urine may enable postsampling synthesis of EtG and ethyl sulfate (EtS) from ethanol, leading to clinical false-posit...
متن کاملPostcollection Synthesis of Ethyl Glucuronide by Bacte- ria in Urine May Cause False Identification of Alcohol
ria in Urine May Cause False Identification of Alcohol Consumption (Department of Clinical Neuroscience, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden; * address correspondence to this author at: Alcohol Laboratory, L7:03, Karolinska University Hospital Solna, SE-171 76 Stockholm, Sweden; fax 46-8-51771532, e-mail [email protected]) Anders Helander,* Ingrid Olss...
متن کاملEthyl glucuronide, ethyl sulfate, and ethanol in urine after intensive exposure to high ethanol content mouthwash.
To determine the degree of ethanol absorption and the resultant formation and urinary excretion of its conjugated metabolites following intensive use of high ethanol content mouthwash, 10 subjects gargled with Listerine(®) antiseptic 4 times daily for 3¼ days. First morning void urine specimens were collected on each of the four study days and post-gargle specimens were collected at 2, 4, and 6...
متن کاملA pharmacokinetic study of ethyl glucuronide in blood and urine: applications to forensic toxicology.
This pharmacokinetic study investigated the kinetics of ethanol and its metabolite ethyl glucuronide (EtG) in blood and urine during the whole time course of absorption and elimination. There are few previous studies on the kinetics of EtG in blood, and we wanted to evaluate whether such knowledge could yield valuable information regarding the time of ethanol ingestion in forensic cases, such a...
متن کاملQuantitation of ethyl glucuronide in serum & urine by gas chromatography - mass spectrometry
BACKGROUND & OBJECTIVES Alcohol misuse has now become a serious public health problem and early intervention is important in minimizing the harm. Biochemical markers of recent and high levels of alcohol consumption can play an important role in providing feedback regarding the health consequences of alcohol misuse. Existing markers are not sensitive to recent consumption and in detecting early ...
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ژورنال
عنوان ژورنال: Laboratory Medicine
سال: 2018
ISSN: 0007-5027,1943-7730
DOI: 10.1093/labmed/lmy008